Progress and Challenges of Understanding Cardiorenal Syndrome Type 3
The pathologies of the kidney and heart have instigated a large number of researchers around the world to try to better understand what the exact connectors responsible for the emergence and establishment of these diseases are. The classification of these pathologies into different types of cardiorenal syndromes (CRSs) over the last 15 years has greatly contributed to understanding pathophysiological and diagnostic aspects, as well as treatment strategies. However, with the advent of new technologies classified as “Omics”, a new range of knowledge and new possibilities have opened up in order to effectively understand the intermediaries between the kidney-heart axis. The universe of micro-RNAs (miRNAs), epigenetic factors, and components present in extracellular vesicles (EVs) have been protagonists in studying different types of CRSs. Thus, the new challenge that is imposed is to select and link the large amount of information generated from the use of large-scale analysis techniques. The present review seeks to present some of the future perspectives related to understanding CRSs, with an emphasis on CRS type 3.
Citação
@online{raquel_silva2023,
author = {Raquel Silva , Neres-Santos and Giovana Marchini , Armentano
and Silva, Jéssica Verônica, Da and Carlos Alexandre , Falconi and
Marcela Sorelli , Carneiro-Ramos},
title = {Progress and Challenges of Understanding Cardiorenal Syndrome
Type 3},
volume = {24},
number = {1},
date = {2023-01-04},
doi = {10.31083/j.rcm2401008},
langid = {pt-BR},
abstract = {The pathologies of the kidney and heart have instigated a
large number of researchers around the world to try to better
understand what the exact connectors responsible for the emergence
and establishment of these diseases are. The classification of these
pathologies into different types of cardiorenal syndromes (CRSs)
over the last 15 years has greatly contributed to understanding
pathophysiological and diagnostic aspects, as well as treatment
strategies. However, with the advent of new technologies classified
as “Omics”, a new range of knowledge and new possibilities have
opened up in order to effectively understand the intermediaries
between the kidney-heart axis. The universe of micro-RNAs (miRNAs),
epigenetic factors, and components present in extracellular vesicles
(EVs) have been protagonists in studying different types of CRSs.
Thus, the new challenge that is imposed is to select and link the
large amount of information generated from the use of large-scale
analysis techniques. The present review seeks to present some of the
future perspectives related to understanding CRSs, with an emphasis
on CRS type 3.}
}